• Cosmedicine Medi-Matte Perfected Mattifying Mositurizer
  • Mattifier for oily skin - Cosmedicine Medi-Matte
  • Best all-day mattifier - Cosmedicine Medi-Matte Moisturizer
40 ml/ 1.35 fl oz
What it is

Long-lasting mattifying daily moisturizer with broad-spectrum SPF

Our mattifying daily moisturizer provides broad-spectrum UVA/UVB sun protection while instantly curbing excess surface sebum and keeping it at bay all day long.

Infused with our proprietary MegaDose® Nutritional Complex, Medi-Matte is a weightless infusion that soaks into the skin to deliver the most potent oil-fighting properties available for a flawless, long-lasting, radiant matte finish.

How It Works

Vaporizes surface sebaceous fluids to regulate oily residue for hours

Chronically problematic skin produces waxy, sticky sebum that creates blockages in pores and stubbornly clings to the skin’s surface. Brimming with anti-aging antioxidants, free radical-fighting plant extracts and our groundbreaking MegaDose® Nutritional Complex, this peerless formula is among the most technologically advanced oil-fighting products on the market. It liquefies biological “glue” so it evaporates at the surface, leaving behind a flawless matte finish.

Our highly complex formulation imparts a protective moisturizing shield of weightless, broad-spectrum SPF and puts a cap on excess oil presence for up to eight hours.

This peerless moisturizer is the most technologically advanced oil-fighting products on the market.

The Science

Increased mattification, reduction in pore size visibility, no significant increase in oil for hours

In clinical tests, subjects experienced a 39% increase in visible mattification and up to 37% reduction in the appearance of pore size with no significant increase in visible surface oil for at least eight hours after use.

INGREDIENTS - Dimethicone/Vinyl Dimethicone Crosspolymer, Trisiloxane, Purified Water, Glycerin, C12-14 Pareth-12, DImethicone, Butylene Glycol, Punica Granatum (Pomegranate) Extract, Tocopheryl Acetate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Oenothera Biennis (Evening Primrose) Root Extract, Sorbitol, Squalane, Yeast Extract, Bambusa Vulgaris (Bamboo) Extract, Pisum Sativum (Pea) Extract, Glucosamine HCl, Panthnyl Ethyl Ether, Magnesium Ascorbyl Phosphate, Polysorbate 60, Isopropylparaben, Isobutylparaben, Butylparaben. »more info

Key Ingredients

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Formulator's Note


Perfected Oil Control Moisturizer Broad Spectrum SPF 20

Pulling off this product was a complicated undertaking. I almost didn’t believe the results myself, because so many people had told me it could not be done. The body needs a slight coating of oil on the skin—and this is where my emollient sunscreen comes in. The trick is to both get rid of the oil you don’t want and keep the oil you want to stay. To test this product, I used a variety of medical instruments that had extremely high magnification capabilities. What we saw shocked all of us in the lab. This product really stands up to scientific scrutiny.


What We Tested

  • Sebum on the surface of the skin
  • Pore diameter
  • Visible shine
  • Skin hydration
  • Acnegenic/comedogenic properties

What Techniques We Used

  • HiScope® video microscope pore size assessment: This technique used optimal magnification of the size and appearance of pores.
  • Sebumeter®: This instrument determines the production of excess sebum excreted on the forehead, which is typically an area of high sebum production, with a specially designed translucent plastic strip that is measured photometrically by a microprocessor. When the strip becomes coated with sebum, the instrument generates readings in micrograms of sebum per square centimeter.
  • Corneometer®: This is the most accurate instrument of its kind on the market and is used to measure hydration levels in the outermost layers of epidermis.

What We Found

  • Baseline visible shine was reduced by an average of 59%.
  • Pore size was reduced by up to 37% immediately following product application, as measured by HiScope® video microscopy.
  • Skin hydration had increased, as measured by the Corneometer®, both immediately after application and after 8 weeks of continued product use.
  • Visible mattification had increased by 39% 8 hours after product application.